Retinal vein occlusion (RVO), a worldwide disease, is a clinical conundrum given its multifactorial etiology, abundant mimickers, and variations. Accurate diagnosis and management are critical as the condition affects more than 28 million patients worldwide and can lead to serious vision loss if not treated promptly. In this book, we have compiled experts to provide a comprehensive overview of the pathophysiology, complications, and management of RVO in an endeavor to provide the highest-quality care.