Pre-Descemet’s endothelial keratoplasty (PDEK) is a new variant in the field of endothelial keratoplasty (EK) that mainly comprises the separation of pre-Descemet's layer (PDL) along with Descemet's membrane (DM)-endothelium complex from the residual donor stroma by the formation of a type-1 bubble. The book “Pre-Descemet’s Endothelial Keratoplasty (PDEK)” outlines a cutting edge procedure in which PDEK graft can be harvested from a donor of any age and grafted into adults. This means endothelial cells would have maximum regenerative capacity. The main goal of this book was to embark upon the minute details of PDEK procedure and its various applications and modifications adopted in the surgical technique. The book comprises of 5 sections which further divided into 25 chapters covering various aspects of PDEK and a DVD with videos showcasing the surgical aspects of handling numerous clinical conditions related to PDEK and its nuances. The aim of this book is to provide the readers with the most comprehensive and current information on PDEK and it is hoped that this edition captures the current state of this vital and dynamic science from international perspective.