This atlas describes an array of tumors and diseases that affect the orbit and associated cranial nerves. Often lacking in radiology residency and fellowship training is teaching of the anatomy of the orbit and cranial nerves, as well as the imaging appearance of orbital tumors and diseases that affect these regions. This atlas fills this gap of knowledge with tumors and diseases encountered and treated at MD Anderson Cancer Center, providing a review of the imaging anatomy and the appearance of the tumors and diseases that should aid in formatting a differential diagnosis.