This book fills a gap in the field of the cranio-orbital lesions, as it deals only with mass lesions involving both the intracranial and intra-orbital compartments. The surgical anatomy, diagnosis, surgical approaches and specified pathological mass lesions are described in detalis. The book includes four parts. Part 1, is devoted to the surgical anatomy of the orbital region. Part 2 to the clinical and neuroradiological examination of the cranio-orbital mass lesions. Part 3 discusses the surgical approaches, both trans-cranial and transorbital, and microscopic and endoscopic, focusing on the surgical techniques, their indications, advantages, limitations and complications. Finally, part 4 discusses the single pathological mass lesions, their anatomo-clinical and radiological aspects and the best surgical approaches. Aim of this book is to illustrate the best surgical approaches according to prevalent intracranial or intra-orbital extension and the type of the mass lesions.